Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma. [...]

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric cancer population. Survival [...]

Feline injection-site sarcoma (FISS), an aggressive iatrogenic subcutaneous malignancy, is challenging to manage clinically and [...]

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood with an unmet clinical [...]

Diffuse intrinsic pontine glioma (DIPG) is a universally fatal childhood cancer of the brain. Despite [...]

In complex, highly unstable genomes such as in osteosarcoma, targeting aberrant checkpoint processes (metabolic, cell [...]

Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. RMS often arise from myogenic [...]

Design of personalized targeted therapies involve modeling of patient sensitivity to various drugs and drug [...]

The prediction of tumor sensitivity to targeted drugs remains a major challenge in the design [...]

Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric brain cancer with [...]

A framework for design of personalized cancer therapy requires the ability to predict the sensitivity [...]

Drugs that target specific proteins are a major paradigm in cancer research. In this article, [...]

Alveolar rhabdomyosarcoma (aRMS) is a myogenic childhood sarcoma frequently associated with a translocation-mediated fusion gene, [...]

The success of targeted anti-cancer drugs are frequently hindered by the lack of knowledge of [...]

Drugs targeting specific kinases are becoming common in cancer research and are a basis for [...]

Genetic Regulatory Networks (GRNs) are frequently modeled as Markov Chains providing the transition probabilities of [...]